Prof. Dr. Ahmed El-Yazbi

Professor
Department of Pharmacology & Toxicology

Biography

Dr. El-Yazbi graduated from the Faculty of Pharmacy, Alexandria University, Egypt in June 2001 with top honors (First in Class, 97% Cumulative grade). He received his PhD degree in Pharmacology from the Faculty of Medicine at the University of Alberta in Edmonton, Canada, in 2007. Dr. El-Yazbi was awarded two fellowships from the Canadian Institutes for Health Research and Alberta Innovates-Health Solutions, during which he conducted a research program studying the regulation of cerebral blood flow at the Hotchkiss Brain Institute and the Libin Heart Institute of the Faculty of Medicine in the University of Calgary, Canada. Ahmed is also Board Certified in Canada as a Clinical Pharmacist licensed in the Province of Alberta as well as being a Board-Certified Pharmacotherapy Specialist (Board of Pharmacy Specialties, Washington DC) with extensive experience in highly specialized pharmaceutical services and hospital pharmacy operations management.

Dr. El-Yazbi has a solid university-level teaching track record with 20 years of experience teaching to pharmacy and medical students in Canadian, Egyptian, and Lebanese universities. He has taught and coordinated 21 courses of various formats at different undergraduate and graduate levels. Furthermore, he has close to 80 original research articles published in international peer-reviewed journals, a number of which are featured as cover stories, Editor’s choice articles, and press releases.. His publications have gathered 1500 citations leading to a h-index of 22.

Dr. El-Yazbi serves on the editorial and review boards of 33 high-impact international journals. He is also an Executive Committee and panel member for a number of international scientific bodies including the American Society of Pharmacology and Experimental Therapeutics and the American College of Clinical Pharmacy. Over the years, Ahmed mentored 18 graduate students (16 MSc and 2 PhD) and accrued a long track record of research funding from multiple Egyptian, American, Canadian, and Lebanese funding agencies. His contributions recognized by invitations to present, speak, and chair scientific sessions in multiple national, regional, and international venues together with an extensive list of academic awards. As well, his trainees consistently receive national and international awards for their work with him.

  • Professor, Faculty of Pharmacy, Alamein International University
  • Professor, Faculty of Medicine, The American University of Beirut
  • Professor, Faculty of Pharmacy, Alexandria University
  • Course Coordinator: Pharmacology for Nursing Students
    Course Level: Undergraduate(Nursing Program)
    Number of Students: 55
    Number of Credits: 3
    Lecture Hours Per Week: 3
    American University of Beiru
  • Instructor: Molecular and Cellular Basis of Medicine
    Course Level: Graduate Medical Education (Med I)
    Number of Students: 100
    American University of Beirut
  • Instructor: The Liver and Gastrointestinal System
    Course Level: Graduate Medical Education (Med I)
    Number of Students: 100
    American University of Beirut
  • Instructor: Endocrinology and Reproduction
    Course Level: Graduate Medical Education (Med II)
    Number of Students: 100
    American University of Beirut
  • Instructor: The Cardiovascular System
    Course Level: Graduate Medical Education (Med II)
    Number of Students: 100
    American University of Beirut
  • Instructor: The Respiratory System Course
    Course Level: Graduate Medical Education (Med II)
    Number of Students: 100
    American University of Beirut
  • Instructor: Biomedical Research Techniques
    Course Level: Post Graduate(PhD in Biomedical Sciences)
    Number of Students: 20
    Number of Credits: 3
    Lecture Hours Per Week: 2
    American University of Beirut
  • Instructor: Graduate level Pharmacology
    Course Level: Graduate(Master Degree in Pharmacology)
    Number of Students: 8
    Number of Credits: 9
    Lecture Hours Per Week: 9
    American University of Beirut
  • Instructor: Graduate Pharmacology for Nursing Students
    Course Level: Graduate(Master Degree in Nursing)
    Number of Students: 10
    Number of Credits: 3
    Lecture Hours Per Week: 3
    American University of Beirut
  • Instructor: Inter-professional Education and Collaboration
    Course Level: Graduate Medical Education (Med II)/Undergraduate Nursing/ Graduate Public Health Program
    Number of Students: 200
    Number of Credits: 1
    Lecture Hours Per Week: 1
    American University of Beirut
  • Course Coordinator: Pharmacotherapy of Cardiovascular Disorders
    Course Level: Fourth year Pharmacy
    Number of Students: 105
    Number of Credits: 3
    Lecture Hours Per Week: 3
    Beirut Arab University
  • Course Coordinator: Pharmacotherapy of Infectious Diseases
    Course Level: Fourth year Pharmacy
    Number of Students: 105
    Number of Credits: 3
    Lecture Hours Per Week: 3
    Beirut Arab University
  • Course Coordinator: Anticoagulation Management
    Course Level: Fifth Year Pharmacy Specialized Elective
    Number of Students: 40
    Number of Credits: 3
    Lecture Hours Per Week: 3
    Beirut Arab University
  • Course Coordinator: Applied Experimental Pharmacology
    Course Level: Graduate (Master Degree in Pharmacology)
    Number of Students: 8
    Number of Credits: 3
    Lecture Hours Per Week: 2
    Lab Hours Per Week: 2
    Alexandria University
  • Course Coordinator: Drug Interactions
    Course Level: Fourth Year Pharmacy
    Number of Students: 120
    Number of Credits: 3
    Lecture Hours Per Week: 3
    Alexandria University
  • Course Coordinator: Advanced Topics in Pharmacotherapy
    Course Level: Fifth Year Pharmacy
    Number of Students: 120
    Number of Credits: 3
    Lecture Hours Per Week: 3
    Alexandria University
  • Instructor: Principles and Mechanisms of Pharmacology
    Course Level: Undergraduate(Bachelor of Health Sciences)
    Number of Students: 20
    Number of Credits: 3
    Lecture Hours Per Week: 3
    University of Calgary
  • Instructor: Pharmacology of Organ Systems Course
    Course Level: Undergraduate(Bachelor of Health Sciences)
    Number of Students: 20
    Number of Credits: 3
    Lecture Hours Per Week: 3
    University of Calgary
  • Instructor: Autonomic Nervous System
    Course Level: Graduate (Mater Degree in Pharmacology)
    Number of Students: 20
    Number of Credits: 3
    Lecture Hours Per Week: 3
    University of Alberta
  • Instructor: Introductory Pharmacology
    Course Level: Undergraduate(General Sciences Program)
    Number of Students: 200
    Number of Credits: 2
    Lecture Hours Per Week: 2
    University of Alberta
  • Instructor: Molecular Pharmacology
    Course Level: Graduate (Master Degree in Pharmacology)
    Number of Students: 8
    Number of Credits: 3
    Lecture Hours Per Week: 3
    University of Alberta

1. Hammoud SH, AlZaim I, Al-Dhaheri Y, Eid AH, El-Yazbi AF. Perirenal Adipose Tissue Inflammation: Novel Insights Linking Metabolic Dysfunction to Renal Diseases. Front Endocrinol In Press. 2. Chaaban I, Hafez H, AlZaim I, Tannous C, Ragab H, Hazzaa A, Ketat S, Ghoneim A, Katary M, Abd-Alhaseeb MM, Zouein FA, Albohy A, Amer AN, El-Yazbi AF, Belal ASF. Transforming Iodoquinol into Broad Spectrum Anti-tumor Leads: Repurposing to Modulate Redox Homeostasis. Bioorg Chem 2021, 113:105035(Co-corresponding Author) 3. Wehbe Z, Hammoud SH, Yassine HM, Fardoun M, El-Yazbi AF, Eid AH. Molecular and Biological Mechanisms Underlying Gender Differences in COVID-19 Severity and Mortality. Front Immunol 2021, 12, 1603. 4. Alaaeddine RA, AlZaim I, Hammoud SH, Arakji A, Eid AH, Abd-Elrahman KS, El-Yazbi AF. The Pleiotropic Effects of Antithrombotic Drugs in the Metabolic-Cardiovascular-Neurodegenerative Disease Continuum: Impact Beyond Reduced Clotting. Clin Sci 2021, 135: 1015-1051. (Corresponding Author) 5. Dwaib HS, AlZaim I, Eid AH, Obeid O, El-Yazbi AF. Modulatory Effect of Intermittent Fasting on Adipose Inflammation: Amelioration of Cardiovascular Dysfunction in Early Metabolic Impairment. Front Pharmacol 2021, 12, 451. (Corresponding Author) 6. Ali AH, Younis N, Abdallah R, Shaer F, Dakroub A, Ayoub M, Iratni R, Yassine HM, Zibara K, Orekhov A, El-Yazbi AF, Eid A. Lipid-Lowering Therapies for Atherosclerosis: Statins, Fibrates, Ezetimibe and PCSK9 monoclonal antibodies. Curr Med Chem. 2021 Feb 21. doi: 10.2174/0929867328666210222092628. Online ahead of print 7. El-Yazbi AF, Khalifa Y, Elkhatib MAW, El-Yazbi AF. Green Analytical Method for the Determination of Sofosbuvir, Ledipasvir, Ribavirin and Complex Silymarin Flavonoids Simultaneously in Biological Fluids. Microchem J, 2021, 164: 105964. (Corresponding Author) 8. Hammoud SH, AlZaim I, Mougharbil N, Koubar S, Eid AH, Eid AA, El-Yazbi AF. Peri-renal adipose inflammation contributes to renal dysfunction in a non-obese prediabetic rat model: Role of anti-diabetic drugs. Biochem Pharmacol. 2021, 186: 114491. doi: 10.1016/j.bcp.2021.114491. (Corresponding Author) 9. Alaaeddine RA, Elzahhar PA, AlZaim I, Abou-Kheir W, Belal ASF, El-Yazbi AF. The emerging role of COX-2, 15-LOX, and PPARγ in metabolic diseases and cancer: An introduction to novel multi-target directed ligands (MTDLs). Curr Med Chem 2021, 28: 2260-2300. (Corresponding Author) 10. Dakroub A, Nasser SA, Kobeissy F, Yassine HM, Orekhov A, Sharifi-Rad J, Iratni R, El-Yazbi AF, Eid AH. Visfatin: An emerging adipocytokine bridging the gap in the evolution of cardiovascular diseases. J Cell Physiol. 2021 doi: 10.1002/jcp.30345. Online ahead of print. 11. Bakkar N-MZ, El-Yazbi AF, Zouein FA, Fares SA. Beat-to-beat Blood Pressure Variability: An Early Predictor of Pathology and Cardiovascular Risk. J Hypertens, 2021, 39: 832-845. 12. Elzahhar PA, Alaaeddine RA, Nassra R, Ismail A, Labib HF, Temraz MG, Belal ASF, El-Yazbi AF. Challenging inflammatory process at molecular, cellular and in vivo levels via some new pyrazolyl thiazolones. J Enz Inh Med Chem, J Enzyme Inhib Med Chem. 2021 36: 669-684. (Corresponding Author) 13. Hammoud S, Wehbe Z, Abdelhady S, Kobeissy F, Eid AH, El-Yazbi AF. Dysregulation of ACE2 Expression and Function in Co-morbid Disease Conditions Possibly Contributes to COVID-19 Complication Severity. Mol Pharm, 2021, 99: 17-28. (Corresponding Author) 14. Rafeh R, Abdelraouf K, Haddad N, Rizk N, El-Yazbi AF. Antimicrobial Therapeutic Drug Monitoring (2020). In Ghazi IM and Cawley MJ (Eds.), Evolving 21st Century Challenges in Infectious Disease. Sharjah: Bentham Science. 3, 263. (Corresponding Author) 15. Bakkar NMZ, Dwaib HS, Fares S, Eid AH, Al-Dhaheri Y, El-Yazbi AF. Cardiac Autonomic Neuropathy: A Progressive Consequence of Chronic Low-Grade Inflammation in Metabolic Disorders. Int J Mol Sci, 2020 21: 9005. (Corresponding Author) 16. Dakroub, A.; A. Nasser, S.; Younis, N.; Bhagani, H.; Al-Dhaheri, Y.; Pintus, G.; Eid, A.A.; El-Yazbi, A.F.; Eid, A.H. Visfatin: A Possible Role in Cardiovasculo-Metabolic Disorders. Cells 2020, 9, 2444. https://doi.org/10.3390/cells9112444

  • 2020/3 – 2023/2 Principal Applicant Vascular Dysfunction in Early Metabolic Challenge due to Thrombo- and Adipose Inflammation: Modulation by DOACs Medical Practice Plan grant, $120,000 (Competitive funding)
  • 2019/8 – 2022/7 Co-applicant Gender Differences in the Interplay between Type 1 Cardiorenal Syndrome and Metabolic Impairment: Underlying Mechanisms Medical Practice Plan grant, $120,000 (Competitive funding)
  • 2018/4 – 2020/3 Principal Applicant Cardiac Autonomic neuropathy and hemodynamic dysfunction as a consequence of adipose inflammation and mild hypercaloric intake: Modification by phosphate supplementation President’s Collaborative Research Stimulus grant, $40,000 (Competitive funding)
  • 2018/1 – 2019/12 Principal Applicant Modulation of metabolic stress-induced neuro-inflammation by oral anti-diabetic drugs: A proposed role for activation of autophagy Conseil National de la Receherche Scientifique grant, $40,000 (Competitive funding)
  • 2017/2 – 2020/1 Principal Applicant Vascular dysfunction as a consequence of high calorie intake: Modulation by oral anti- hyperglycemic drugs Medical Practice Plan grant, $120,000 (Competitive funding)
  • 2014/9 – 2016/10 Co-applicant Effect of hyperlipidemia on posaconazole-vincristine drug-drug interaction in rat Science and Technology Development Fund Young Investigator Grants
 CAD $150,000 (Competitive funding)
  • 2014/6 – 2016/5 Co-applicant Establishing a cell culture laboratory in the Medical Campus in Alexandria University Alexandria University Research Fund CAD $100,000 (Competitive funding)
  • 2014/4 – 2016/3 Co-applicant Heme oxygenase modulation of cardiovascular derangements evoked by the combined cyclosporine/NSAIDs regimen in rats: Functional, structural, and molecular studies Alexandria University Research Fund CAD $30,000 (Competitive funding)