Asst. Prof. Dr. Ingy Abdallah

Assistant Professor
Department of Pharmacognosy

Biography

Dr. Ingy is currently an Assistant Professor at Faculty of Pharmacy. In June 2008, she finished her BSc in Pharmaceutical Sciences at Faculty of Pharmacy, Alexandria University in Egypt. She started teaching undergraduate Pharmacy students while pursuing a research master on Pharmacognosy and Natural Product Chemistry. She obtained her MSc degree from Faculty of Pharmacy, Alexandria University on September 2012. Following that, she was successfully awarded an Erasmus Mundus, Fatima Al Fihri PhD scholarship to the University of Groningen (September 2013).

On May 2018, she completed her PhD degree in the Department of Chemical and Pharmaceutical Biology in Groningen Research Institute of Pharmacy (GRIP) University of Groningen, The Netherlands. Ingy is passionate about research and teaching. She has experience in teaching several undergraduate and postgraduate Pharmacy courses in University of Alexandria, University of Groningen, Arab Academy for Science, Technology & Maritime Transport and AlAlamein International University. Her research interests encompass natural products chemistry, molecular biology, Enzyme, genetic & metabolic engineering, “omics” and cancer targeted therapy. She has several publications in internationally recognized peer reviewed highly-ranked journals. She also actively participates in numerous international conferences.

  • Assistant lecturer at Faculty of Pharmacy, Alexandria University, Egypt from September 2008 till August 2013
  • PhD researcher at University of Groningen, The Netherlands from September 2013 till May 2018
  • Post-doctoral fellow at University of Groningen, The Netherlands from September 2018 till August 2019
  • Assistant Professor at College of Pharmacy, Arab Academy for Science, Technology & Maritime Transport, Alexandria, Egypt from September 2019 till February 2020
  • Assistant Professor at Faculty of Pharmacy, Alexandria University, Egypt from September 2019 till present
  • Assistant Professor at Faculty of Pharmacy, AlAlamein International University, Egypt from October 2020 till present
  • Assistant lecturer at Faculty of Pharmacy, Alexandria University, Egypt from September 2008 till August 2013 (Courses: Botany & medicinal plants, Pharmacognosy & medicinal plants, Phytochemistry, Applied Pharmacognosy, Chromatography).
  • Post-doctoral fellow at University of Groningen, The Netherlands from September 2018 till August 2019 (Courses: Organic and Biosynthesis, Infections and tumors, Pharmaceutical Biology and Biotechnology, Medicinal natural products).
  • Assistant Professor at College of Pharmacy, Arab Academy for Science, Technology & Maritime Transport, Alexandria, Egypt from September 2019 till February 2020 (Courses: Medicinal Plants).
  • Assistant Professor at Faculty of Pharmacy, Alexandria University, Egypt from September 2019 till present (Courses: Medicinal Plants, Pharmacognosy).
  • Assistant Professor at Faculty of Pharmacy, AlAlamein International University, Egypt from October 2020 till present (Courses: Botany and Medicinal Plants).

1. Pramastya, H., Xue, D., Abdallah, I.I., Setroikromo, R., & Quax, W.J., (2021) High level production of amorphadiene using Bacillus subtilis as an optimized terpenoid cell factory. New Biotechnology, 60, 159-167.

2. Song, Y., Guan, Z., van Merkerk, R., Pramastya, H., Abdallah, I.I., Setroikromo, R., & Quax, W.J., (2020) Production of squalene in Bacillus subtilis by squalene synthase screening and metabolic engineering. Journal of Agricultural and Food Chemistry, 68, 4447−4455.

3. Abdallah, I.I., Xue, D., Pramastya, H., van Merkerk, R., Setroikromo, R., & Quax, W.J., (2020) A regulated synthetic operon facilitates stable overexpression of multigene terpenoid pathway in Bacillus subtilis. Journal of Industrial Microbiology and Biotechnology, 47, 243–249.

4. Abdallah, I.I., Pramastya, H., van Merkerk, R., Sukrasno, & Quax, W.J., (2019) Metabolic Engineering of Bacillus subtilis toward taxadiene biosynthesis as the first committed step for Taxol production. Frontiers in Microbiology, 10, 218

5. Abdallah, I.I., van Merkerk, R., Klumpenaar, E., & Quax, W.J., (2018). Catalysis of amorpha-4,11-diene synthase unraveled and improved by mutability landscape guided engineering. Scientific Reports, 8, 9961.

6. Abdallah, I.I. & Quax, W.J. (2018). Insights into the structure-function relations of amorpha-4,11- diene synthase. Biotarget, 2.

7. Abdallah, I.I. & Quax, W.J. (2017). A glimpse into the biosynthesis of terpenoids. In International Conference on Natural Resources and Life Sciences (NRLS-2016). KnE Life Sciences, 81-89.

8. Abdallah, I.I., Czepnik, M., van Merkerk, R., & Quax, W.J. (2016). Insights into the Three-Dimensional Structure of Amorpha-4,11-diene Synthase and Probing of Plasticity Residues. Journal of Natural Products, 79(10), 2455-2463.

9. Guan, Z., Xue, D., Abdallah, I.I., Dijkshoorn, L., Setroikromo, R., Lv, G., & Quax, W.J. (2015). Metabolic engineering of Bacillus subtilis for terpenoid production. Applied Microbiology and Biotechnology, 99(22), 9395-9406.

10. Xue, D., Abdallah, I.I., de Haan, I.E.M., Sibbald, M.J.J.B., & Quax, W.J. (2015). Enhanced C30 carotenoid production in Bacillus subtilis by systematic overexpression of MEP pathway genes. Applied Microbiology and Biotechnology, 99(14), 5907-5915.

11. Harraz, F.M., Ghazy, N.M., Hammoda, H.M., Nafeaa, A.A., & Abdallah, I.I. (2015). Hepatoprotective and antioxidant activities of Tribulus terrestris. Journal of Physiology and Pharmacology Advances, 5(11), 787-794.

12. Hammoda, H.M., Ghazy, N.M., Harraz, F.M., Radwan, M.M., ElSohly, M.A., & Abdallah, I.I. (2013). Chemical constituents from Tribulus terrestris and screening of their antioxidant activity. Phytochemistry, 92, 153-159.

1. Abdallah, I.I., Pramastya, H., Xue, D., van Merkerk, R., Setroikromo, R., Tepper, P.G. & Quax, W.J., Engineering a microbial cell factory on the road to biosynthesis of the terpenoids, Taxol and Artemisinin.
Second PUA International Conference “Multidisciplinary Approaches in Pharmaceutical Sciences” (ICMAPS 2020), Alexandria, Egypt. March 2020
Conference presentation

2. International Conference on Pharmaceutical & Healthcare Sciences (PHS 2019), Alexandria, Egypt. November 2019
Attendance

3. Abdallah, I.I., Pramastya, H., Xue, D., van Merkerk, R., Setroikromo, R., & Quax, W.J., Metabolic engineering of Bacillus subtilis toward biosynthesis of the terpenoids, Taxol and artemisinin.
BACELL, Ljubljana, Slovenia. April 2019
Conference presentation

4. Abdallah, I.I., van Merkerk, R., Klumpenaar, E., & Quax, W.J., The path to improved production of the antimalarial artemisinin.
FIGON Dutch Medicine Days, Ede, The Netherlands. October 2018
Conference presentation

5. Abdallah, I.I., van Merkerk, R., Klumpenaar, E. & Quax, W.J., Engineering amorphadiene synthase, the terpene cyclase producing artemisinin.
CHAINS, Veldhoven, The Netherlands. December 2017
Conference presentation

6. Abdallah, I.I., Czepnik, M., van Merkerk, R., & Quax, W.J., Amorphadiene Synthase: A Step Forward in Unraveling the Enigma of its Catalytic Mechanism.
CHAINS, Veldhoven, The Netherlands. December 2016
Conference poster

7. Abdallah, I.I., Xue, D., Guan, Z. & Quax, W.J., Engineering Bacillus subtilis as cell factory for terpenoid production.
European Symposium on Biochemical Engineering Sciences (ESBES), Dublin Ireland. September 2016
Conference presentation

8. Guan, Z., Abdallah, I.I., Xue, D., Aldakkak, K. & Quax, W.J., Non-targeted metabolomics indicates the potential of Bacillus subtilis for terpenoid biosynthesis.
BACELL & Symposium on Central Carbon Metabolism, Paris, France. April 2016
Conference presentation

9. Abdallah, I.I., Xue, D. & Quax, W.J., Engineering Bacillus subtilis as cell factory for terpenoid production.
International Conference on Metabolic Engineering in Bacteria & BACELL, Amsterdam, The Netherlands. April 2015
Conference presentation (Award for best oral presentation)

10. Abdallah, I.I. & Quax, W.J., Metabolic engineering of Bacillus subtilis for terpenoid Production.
Bacterial Cell Surface Platform at Leiden, The Netherlands. March 2015
Conference presentation

11. Abdallah, I.I. & Quax, W.J., Bacillus subtilis as cell factory for terpenoids production.
PROMYSE EU project meeting (FP7-KBBE-2011-5 grant 289540) at Barcelona, Spain. December 2014
Presentation

12. Abdallah, I.I. & Quax, W.J., MEP pathway modulation for terpenoids production in Bacillus subtilis.
PROMYSE EU project meeting (FP7-KBBE-2011-5 grant 289540) at Oegstgeest, The Netherlands. June 2014
Presentation

13. PROMYSE EU project meeting (FP7-KBBE-2011-5 grant 289540) at Zurich, Switzerland. January 2014
Attendance

14. Hammoda, H.M., Ghazy, N.M., Harraz, F.M., Radwan, M.M., El Sohly, M.A. & Abdallah, I.I., Phytochemical and Antioxidant Investigation of Tribulus terrestris. Planta Med. 2013, 79(05), P56 at 12th Annual Oxford International Conference on the Science of Botanicals (ICSB), University of Mississippi, USA

15. BioVision “New life sciences: Linking science to society” conference at Alexandria, Egypt. April 2012
Attendance

1. PhD scholarship to University of Groningen, The Netherlands: Erasmus Mundus Action 2, Strand 1, Fatima Al Fihri project. (on competitive basis)

2. PhD scholarship: The Ubbo Emmius scholarship, University of Groningen, The Netherlands.

3. Post-doctoral fellowship at Groningen Research Institute of Pharmacy, University of Groningen, The Netherlands. (on competitive basis)

4. Active member in European project entitled: Products from methanol by synthetic cell factories [PROMYSE] (EU FP-7 grant FP7-KBBE-2011-3-6-04-289540) 2013-2014.