Assoc. Prof. Dr. Mohamed Nabil Abd Al Moaty

Associate Professor
Department of Chemistry

Biography

Dr. Mohamed Nabil Abd Al Moaty, Associate Professor of Organic Chemistry. Completed his Ph.D. in Organic Chemistry in 2016 at the Faculty of Science, Alexandria University.

His research interests include the design and synthesis of biologically active compounds, such as nucleosides and heterocyclic compounds, with a wide range of biological effects. With over 185 citations and an H-index of 7, Dr. Abd Al Moaty has made significant contributions to the scientific community, publishing more than 15 articles in highly ranked international journals. His research involves the synthesis, characterization, and spectral studies of organic compounds, utilizing advanced instruments such as NMR, HPLC, FTIR, and polarimeters. He has also supervised several M.Sc. and Ph.D. theses within the Faculty of Science at Alexandria University.

He is an associate editor for the Alexandria Journal of Science and Technology (AJST) as well as a reviewer for journals such as, Journal of Heterocyclic Chemistry, Chemistry Select and Chemistry and Biodiversity.

  • Associate Professor of Organic Chemistry, Faculty of Science, Alamein International University, Egypt (September 2025 – Present)
  • Associate Professor of Organic Chemistry, Faculty of Science, Alexandria University, Egypt (September 2022 – Present) (Fully delegated to AIU)
  • Lecturer of Organic Chemistry, Faculty of Science, Alexandria University, Egypt (August 2016 – September 2022)
  • Assistant Lecturer, Chemistry Department, Faculty of Science, Alexandria University, Egypt (January 2012 – 2016)
  • Teaching Assistant, Chemistry Department, Faculty of Science, Alexandria University, Egypt (August 2007 – 2011)
  • Executive Manager, Central Laboratory, Faculty of Science, Alexandria University (2019/2020).
  • Chemistry of Carbohydrates
  • Chemotherapy
  • Organic chemistry 1
  • Biomolecules
  • Organic Chemistry 2
  • Amino acids and Proteins
  • Medicinal Chemistry
  • Natural Products and raw materials
  • Fundamentals of Organic Chemistry
  • Chemistry of Heterocyclic Compounds
  • Lipids and Nucleic acids
  • Rubber, Soap and Detergents
  • Spectroscopy

1. M.A. El-Atawy, Mohamed N. Abd Al Moaty and A. Amer. A Global Perspective on a Review of a Three-Year C-Nucleosides Development: 2009-2011. American Journal of Chemistry 2013, 3(4), 77-95.

2. E.S.H El Ashry, L.F. Awad, S. M. Soliman, Mohamed N. Abd Al Moaty, H.H. Ghabbour and A. Barakat. Tautomerism aspect of thione-thiol combined with spectral investigation of some 4-amino-5-methyl-1,2,4-triazole-3-thione Schiff’s bases. Journal of Molecular Structure 2017, 1146, 432-440.

3. E.S.H El Ashry, L.F. Awad, Mohamed N. Abd Al Moaty, H.H. Ghabbour and A. Barakat. Stereoselective synthesis of novel thioglycosyl heterocycles. Journal of Molecular Structure 2018, 1152, 87-95.

4. E.S.H El Ashry, L.F. Awad, Mohamed N. Abd Al Moaty and O.K. Bdeewy. A novel trans-amination process in 3-arylamino- 5,5 dimethylcyclohex-2-en-1-one with nucleophiles and antimicrobial activity of selected products. Mediterranean Journal of Chemistry 2019, 7(6), 452-462.

5. E.S.H El Ashry, L.F. Awad, M. Teleb, N.A. Ibrahim, M.M. Abu-Serie and Mohamed N. Abd Al Moaty. Structure-based design and optimization of pyrimidine- and 1,2,4-triazolo [4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology, Bioorganic Chemistry 2020, 96, 103616.

6. F.F. Albelwi, M. Teleb, M.M. Abu-Serie, Mohamed N. Abd Al Moaty, M.S. Alsubaie, M.A. Zakaria, Y. El Kilany, M.R. Aouad, M. Hagar, N. Rezki. Halting Tumor Progression via Novel Non-Hydroxamate Triazole-Based Mannich Bases MMP-2/9 Inhibitors; Design, Microwave-Assisted Synthesis, and Biological Evaluation. International Journal of Molecular Science 2021, 22, 10324.

7. E.S.H El Ashry, L.F. Awad, M.E.I. Badawy, E.I. Rabea, N.A. Ibrahim and Mohamed N. Abd Al Moaty. Synthesis, antibacterial, antioxidant, and molecular docking studies of 6-methylpyrimidin-4(3H)-one and oxo-1,2,4-triazolo[4,3-a]pyrimidine derivatives. Journal of Molecular Structure 2022, 1249, 131551.

8. E.S.H El Ashry, M.K. Farahat, L.F. Awad, M. Balbaa, H. Yusef, M.E.I. Badawy and Mohamed N. Abd Al Moaty. New 4-(arylidene)amino-1,2,4-traizole-5-thiol derivatives and their acyclo thioglycosides as α-glucosidase and α-amylase inhibitors: Design, synthesis, and molecular modelling studies. Journal of Molecular Structure 2022, 1259, 132733.

9. Mohamed N. Abd Al Moaty, E.S.H El Ashry, L.F. Awad, N.A. Ibrahim, M.M. Abu-Serie, A. Barakat, M.S. Altowyan and M. Teleb. Enhancing the Anticancer Potential of Targeting Tumor-Associated Metalloenzymes via VEGFR Inhibition by New Triazolo[4,3-a]pyrimidinone Acyclo C-Nucleosides Multitarget Agents. Molecules 2022, 27, 2422.

10. Mohamed N. Abd Al Moaty, E.S.H El Ashry, L.F. Awad, A. Mostafa, M.M. Abu-Serie and M. Teleb. Harnessing ROS-induced oxidative stress for halting colorectal cancer via thiazolidinedione-based SOD inhibitors. ACS OMEGA, Accepted 26 May 2022. Doi.org/10.1021/acsomega.2c02410.

11. Rabab A. Dorgham, Mohamed Nabil Abd Al Moaty, Khim Phin Chong and Bassma H. Elwakil, Molasses-Silver Nanoparticles: Synthesis, Optimization, Characterization and Antibiofilm Activity, International Journal of Molecular Sciences 2022, 23, 10243. https://doi.org/10.3390/ijms231810243.

12. Mohamed Nabil Abd Al Moaty, Y. El Kilany, L. F. Awad, N. A. Ibrahim, M. M. Abu‐Serie, A. El‐Yazbi, M. Teleb, Discovery of novel benzimidazole acyclic C‐nucleoside DNA intercalators halting breast cancer growth. Arch. Pharm. 2023, e2300454. https://doi.org/10.1002/ardp.202300454

13. Mohamed N. Abd Al Moaty, Yeldez El Kilany, Laila F. Awad, Saied M. Soliman, Assem Barakat, Nihal A. Ibrahim, Marwa M. Abu-Serie, Matti Haukka, Amira El-Yazbi, and Mohamed Teleb, Triggering Breast Cancer Apoptosis via Cyclin-Dependent Kinase Inhibition and DNA Damage by Novel Pyrimidinone and 1,2,4-Triazolo[4,3‑a]pyrimidinone Derivatives, ACS OMEGA 2024, 9, 21042-21057. https://doi.org/10.1021/acsomega.4c00466

14. Mohammed Salah Ayoup, Rabia E. Alashhab, Saied M. Soliman, Hamida Abdel-Hamid, David B. Cordes, Aidan P. McKay, Doaa A. Ghareeb, Aliaa Masoud, Asmaa E. Kassab, Mohamed N. Abd Al Moaty, Novel Ag(I)-based 1,2,4-Oxadiazole Complexes: Synthesis, X-Ray Crystal Structure, and Biological Evaluation as Anticancer Candidates, Applied Organometallic Chemistry 2025, 39(2), 7804. https://doi.org/10.1002/aoc.7804

15. Mohammed Salah Ayoup, Rabia E. Alashhab, Hamida Abdel-Hamid, Doaa A. Ghareeb, Aliaa Masoud, Amr Sonousi, Asmaa E. Kassab, and Mohamed N. Abd Al Moaty. Design, Synthesis, Molecular Docking, and Biological Evaluation of Novel 1, 2, 4-Oxadiazole-Based Derivatives as Inhibitors of Trypsin, ALDH2, and iNOS. Russian Journal of Bioorganic Chemistry 2025, 51(3), 1171-1188.

1. Participant, NASIC-UiTM Workshop on Drug Development from Indigenous Plants, Malaysia (4th-7th October 2016)

1- Principal Investigator for Project No. 6388: Modernization and Development of the Nuclear Magnetic Resonance Device, Faculty of Science, Alexandria University. Funded by the Academy of Scientific Research and Technology.

Google Scholar Profile
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Scopus Profile
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